WebMar 7, 2024 · Daptomycin is a lipopeptide antimicrobial with activity against gram-positive organisms, including antimicrobial-resistant pathogens such as methicillin-resistant … WebApr 25, 2024 · Vancomycin (VAN) and daptomycin (DAP) are approved as a monotherapy for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia.
Association of Higher Daptomycin Dose (7 mg/kg or Greater) with ...
WebJul 22, 2024 · Two case reports acknowledged successful treatment of a daptomycin non-susceptible bacteremia with daptomycin 10 mg/kg daily plus sulfamethoxazole-trimethoprim 8 mg/kg daily divided every 8 hours (8). In addition, a case series of 26 patients with MRSA bacteremia caused by bone and joint infections identified 24 out of 26 … WebDaptomycin is a lipopeptide antibiotic with potent in vitro activity against gram-positive cocci, including Staphylococcus aureus. This study evaluated the in vitro and in vivo efficacies of daptomycin against two clinical isolates: methicillin-resistant S. aureus (MRSA) 277 (vancomycin MIC, 2 g/ml) and glycopeptide-intermedi- church of the brethren benefit trust
Daptomycin: An overview - UpToDate
WebDaptomycin Dosing and Use Guidelines Dosing: Soft tissue infection = 4 mg/kg every 24 hours Staphylococcus aureus bacteremia, other deep-seated infections = 6 mg/kg … WebAbstract: Bacteremia due to Staphylococcus aureus, especially methicillin-resistant S. aureus (MRSA), complicates the clinical course of liver transplantation and is associated … WebMay 29, 2024 · Daptomycin is a rapidly acting bactericidal antibiotic that is approved for the treatment of Staphylococcus aureus bacteremia as monotherapy but has not been shown to be superior to the current standard of care. As demonstrated in vitro, the addition of daptomycin to beta-lactam therapy may result in enhanced anti-staphylococcal activity. church of the brethren cerro gordo