WebApr 10, 2024 · There is a need for innovative pharmaceutical intervention in light of the increasing prevalence of metabolic disease and cardiovascular disease. The kidneys’ sodium-glucose cotransporter 2 inhibitors (SGLT2) receptors are targeted to reduce glucose reabsorption by SGLT2. Patients with type 2 diabetes mellitus (T2DM) benefit the most … Web1 day ago · Among the complications of diabetes, cardiovascular events and cardiac insufficiency are considered two of the most important causes of death. Experimental and clinical evidence supports the effectiveness of SGLT2i for improving cardiac dysfunction. SGLT2i treatment benefits metabolism, microcirculation, mitochondrial function, fibrosis, …
Diabetic ketoacidosis and hyperosmolar hyperglycemic state
WebAug 1, 2024 · Introduction: Diabetic ketoacidosis (DKA) is highly prevalent in pediatric patients with both newly diagnosed and established diabetes. Hypertriglyceridemia is a rare, adverse complication. Case Report: A previously healthy 14 year old female presented to the emergency room with 3 days of headaches. Her initial vitals: blood pressure 130/94, … WebIn peripheral tissues, such as the liver, lipolysis occurs to free fatty acids, resulting in further production of excess ketones. Thereby, causing ketosis and metabolic acidosis. Symptoms of diabetic ketoacidosis usually … high heels protectors grass
Diabetic ketoacidosis - Symptoms and causes - Mayo Clinic
WebNov 23, 2024 · The anion gap closed, and the acidosis resolved after two days. Serum triglycerides decreased to less than 1,000 mg/dL on day 6 of hospitalization, allowing … WebAug 30, 2024 · Abstract. Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to insulin. Because insulin release and activity are essential processes for … WebAug 8, 2024 · Ketoacidosis is a metabolic state associated with pathologically high serum and urine concentrations of ketone bodies, namely acetone, acetoacetate, and beta-hydroxybutyrate. ... which is responsible for the breakdown of triglycerides to free fatty acid and glycerol. The clinically relevant ketoacidoses to be discussed include diabetic ... how internet influence teenagers